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A theoretical model of inflammation- and mechanotransduction-driven asthmatic airway remodelling
Inflammation, airway hyper-responsiveness and airway remodelling are well-established hallmarks of asthma, but their inter-relationships remain elusive. In order to obtain a better understanding of their inter-dependence, we develop a mechanochemical morphoelastic model of the airway wall accounting...
Autores principales: | Hill, Michael R., Philp, Christopher J., Billington, Charlotte K., Tatler, Amanda L., Johnson, Simon R., O’Dea, Reuben D., Brook, Bindi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154265/ https://www.ncbi.nlm.nih.gov/pubmed/29968161 http://dx.doi.org/10.1007/s10237-018-1037-4 |
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