Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants

Mycothiol (MSH) and ergothioneine (ERG) are thiols able to compensate for each other to protect mycobacteria against oxidative stress. Gamma-glutamylcysteine (GGC), another thiol and an intermediate in ERG biosynthesis has detoxification abilities. Five enzymes are involved in ERG biosynthesis, name...

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Detalles Bibliográficos
Autores principales: Sao Emani, C., Williams, M. J., Van Helden, P. D., Taylor, M. J. C., Carolis, C., Wiid, I. J., Baker, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154287/
https://www.ncbi.nlm.nih.gov/pubmed/30251996
http://dx.doi.org/10.1038/sdata.2018.184

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