Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer

Safety and clinical feasibility of injecting a novel liquid fiducial marker for use in image guided radiotherapy in 15 patients with non-small cell lung cancer are reported. No major safety or toxicity issues were encountered. Markers present at start of radiotherapy remained visible in cone beam co...

Descripción completa

Detalles Bibliográficos
Autores principales: de Blanck, Steen Riisgaard, Rydhög, Jonas Scherman, Larsen, Klaus Richter, Clementsen, Paul Frost, Josipovic, Mirjana, Aznar, Marianne Camille, af Rosenschöld, Per Munck, Jølck, Rasmus Irming, Specht, Lena, Andresen, Thomas Lars, Persson, Gitte Fredberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154396/
https://www.ncbi.nlm.nih.gov/pubmed/30258990
http://dx.doi.org/10.1016/j.ctro.2018.07.004
_version_ 1783357681596104704
author de Blanck, Steen Riisgaard
Rydhög, Jonas Scherman
Larsen, Klaus Richter
Clementsen, Paul Frost
Josipovic, Mirjana
Aznar, Marianne Camille
af Rosenschöld, Per Munck
Jølck, Rasmus Irming
Specht, Lena
Andresen, Thomas Lars
Persson, Gitte Fredberg
author_facet de Blanck, Steen Riisgaard
Rydhög, Jonas Scherman
Larsen, Klaus Richter
Clementsen, Paul Frost
Josipovic, Mirjana
Aznar, Marianne Camille
af Rosenschöld, Per Munck
Jølck, Rasmus Irming
Specht, Lena
Andresen, Thomas Lars
Persson, Gitte Fredberg
author_sort de Blanck, Steen Riisgaard
collection PubMed
description Safety and clinical feasibility of injecting a novel liquid fiducial marker for use in image guided radiotherapy in 15 patients with non-small cell lung cancer are reported. No major safety or toxicity issues were encountered. Markers present at start of radiotherapy remained visible in cone beam computed tomography and fluoroscopy images throughout the treatment course and on computed tomography images during follow-up (0–38 months). Marker volume reduction was seen until 9 months after treatment, after which no further marker breakdown was found. No post-treatment migration or marker related complications were found.
format Online
Article
Text
id pubmed-6154396
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-61543962018-09-26 Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer de Blanck, Steen Riisgaard Rydhög, Jonas Scherman Larsen, Klaus Richter Clementsen, Paul Frost Josipovic, Mirjana Aznar, Marianne Camille af Rosenschöld, Per Munck Jølck, Rasmus Irming Specht, Lena Andresen, Thomas Lars Persson, Gitte Fredberg Clin Transl Radiat Oncol Article Safety and clinical feasibility of injecting a novel liquid fiducial marker for use in image guided radiotherapy in 15 patients with non-small cell lung cancer are reported. No major safety or toxicity issues were encountered. Markers present at start of radiotherapy remained visible in cone beam computed tomography and fluoroscopy images throughout the treatment course and on computed tomography images during follow-up (0–38 months). Marker volume reduction was seen until 9 months after treatment, after which no further marker breakdown was found. No post-treatment migration or marker related complications were found. Elsevier 2018-08-02 /pmc/articles/PMC6154396/ /pubmed/30258990 http://dx.doi.org/10.1016/j.ctro.2018.07.004 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
de Blanck, Steen Riisgaard
Rydhög, Jonas Scherman
Larsen, Klaus Richter
Clementsen, Paul Frost
Josipovic, Mirjana
Aznar, Marianne Camille
af Rosenschöld, Per Munck
Jølck, Rasmus Irming
Specht, Lena
Andresen, Thomas Lars
Persson, Gitte Fredberg
Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title_full Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title_fullStr Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title_full_unstemmed Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title_short Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
title_sort long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154396/
https://www.ncbi.nlm.nih.gov/pubmed/30258990
http://dx.doi.org/10.1016/j.ctro.2018.07.004
work_keys_str_mv AT deblancksteenriisgaard longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT rydhogjonasscherman longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT larsenklausrichter longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT clementsenpaulfrost longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT josipovicmirjana longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT aznarmariannecamille longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT afrosenscholdpermunck longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT jølckrasmusirming longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT spechtlena longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT andresenthomaslars longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer
AT perssongittefredberg longtermsafetyandvisibilityofanovelliquidfiducialmarkerforuseinimageguidedradiotherapyofnonsmallcelllungcancer

Ejemplares similares