Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia

The peptide hormone hepcidin is a key controller of systemic iron homeostasis, and its expression in the liver is mainly regulated by bone morphogenetic proteins (BMPs), which are heparin binding proteins. In fact, heparins are strong suppressors of hepcidin expression in hepatic cell lines that act...

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Detalles Bibliográficos
Autores principales: Poli, Maura, Asperti, Michela, Ruzzenenti, Paola, Naggi, Annamaria, Arosio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154463/
https://www.ncbi.nlm.nih.gov/pubmed/28397746
http://dx.doi.org/10.3390/molecules22040598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154463/
https://www.ncbi.nlm.nih.gov/pubmed/28397746
http://dx.doi.org/10.3390/molecules22040598

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