Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel Isatin-Thiazole Derivatives as α-Glucosidase Inhibitors

A series of novel isatin-thiazole derivatives were synthesized and screened for their in vitro α-glucosidase inhibitory activity. These compounds displayed a varying degree of α-glucosidase inhibitory activity with IC(50) ranging from 5.36 ± 0.13 to 35.76 ± 0.31 μm as compared to the standard drug a...

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Detalles Bibliográficos
Autores principales: Xie, Zhenzhen, Wang, Guangcheng, Wang, Jing, Chen, Ming, Peng, Yaping, Li, Luyao, Deng, Bing, Chen, Shan, Li, Wenbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154535/
https://www.ncbi.nlm.nih.gov/pubmed/28425975
http://dx.doi.org/10.3390/molecules22040659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154535/
https://www.ncbi.nlm.nih.gov/pubmed/28425975
http://dx.doi.org/10.3390/molecules22040659

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