The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions

A facile, green, and efficient method for the direct oxidative amination of benzoxazoles using heterocyclic ionic liquid as catalyst has been developed. The reaction proceeded smoothly at room temperature and gave the desirable 2-aminobenzoxazoles with good to excellent yields (up to 97%). The catal...

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Detalles Bibliográficos
Autores principales: Zhou, Ya, Liu, Zhiqing, Yuan, Tingting, Huang, Jianbin, Liu, Chenjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154564/
https://www.ncbi.nlm.nih.gov/pubmed/28368328
http://dx.doi.org/10.3390/molecules22040576
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author Zhou, Ya
Liu, Zhiqing
Yuan, Tingting
Huang, Jianbin
Liu, Chenjiang
author_facet Zhou, Ya
Liu, Zhiqing
Yuan, Tingting
Huang, Jianbin
Liu, Chenjiang
author_sort Zhou, Ya
collection PubMed
description A facile, green, and efficient method for the direct oxidative amination of benzoxazoles using heterocyclic ionic liquid as catalyst has been developed. The reaction proceeded smoothly at room temperature and gave the desirable 2-aminobenzoxazoles with good to excellent yields (up to 97%). The catalyst 1-butylpyridinium iodide can be easily recycled and reused with similar efficacies for at least four cycles.
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spelling pubmed-61545642018-11-13 The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions Zhou, Ya Liu, Zhiqing Yuan, Tingting Huang, Jianbin Liu, Chenjiang Molecules Article A facile, green, and efficient method for the direct oxidative amination of benzoxazoles using heterocyclic ionic liquid as catalyst has been developed. The reaction proceeded smoothly at room temperature and gave the desirable 2-aminobenzoxazoles with good to excellent yields (up to 97%). The catalyst 1-butylpyridinium iodide can be easily recycled and reused with similar efficacies for at least four cycles. MDPI 2017-04-02 /pmc/articles/PMC6154564/ /pubmed/28368328 http://dx.doi.org/10.3390/molecules22040576 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhou, Ya
Liu, Zhiqing
Yuan, Tingting
Huang, Jianbin
Liu, Chenjiang
The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title_full The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title_fullStr The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title_full_unstemmed The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title_short The Synthesis of 2-Aminobenzoxazoles Using Reusable Ionic Liquid as a Green Catalyst under Mild Conditions
title_sort synthesis of 2-aminobenzoxazoles using reusable ionic liquid as a green catalyst under mild conditions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154564/
https://www.ncbi.nlm.nih.gov/pubmed/28368328
http://dx.doi.org/10.3390/molecules22040576
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