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Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography

Coronary artery disease (CAD) is the leading cause of death in the world. Myocardial perfusion imaging (MPI) plays a significant role in non-invasive diagnosis and prognosis of CAD. However, neither single-photon emission computed tomography nor positron emission tomography clinical MPI agents can a...

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Autores principales: Mou, Tiantian, Zhang, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154634/
https://www.ncbi.nlm.nih.gov/pubmed/28358340
http://dx.doi.org/10.3390/molecules22040562
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author Mou, Tiantian
Zhang, Xianzhong
author_facet Mou, Tiantian
Zhang, Xianzhong
author_sort Mou, Tiantian
collection PubMed
description Coronary artery disease (CAD) is the leading cause of death in the world. Myocardial perfusion imaging (MPI) plays a significant role in non-invasive diagnosis and prognosis of CAD. However, neither single-photon emission computed tomography nor positron emission tomography clinical MPI agents can absolutely satisfy the demands of clinical practice. In the past decades, tremendous developments happened in the field of (18)F-labeled MPI tracers. This review summarizes the current state of (18)F-labeled MPI tracers, basic research data of those tracers, and the future direction of MPI tracer research.
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spelling pubmed-61546342018-11-13 Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography Mou, Tiantian Zhang, Xianzhong Molecules Review Coronary artery disease (CAD) is the leading cause of death in the world. Myocardial perfusion imaging (MPI) plays a significant role in non-invasive diagnosis and prognosis of CAD. However, neither single-photon emission computed tomography nor positron emission tomography clinical MPI agents can absolutely satisfy the demands of clinical practice. In the past decades, tremendous developments happened in the field of (18)F-labeled MPI tracers. This review summarizes the current state of (18)F-labeled MPI tracers, basic research data of those tracers, and the future direction of MPI tracer research. MDPI 2017-03-30 /pmc/articles/PMC6154634/ /pubmed/28358340 http://dx.doi.org/10.3390/molecules22040562 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mou, Tiantian
Zhang, Xianzhong
Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title_full Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title_fullStr Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title_full_unstemmed Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title_short Research Progress on (18)F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography
title_sort research progress on (18)f-labeled agents for imaging of myocardial perfusion with positron emission tomography
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154634/
https://www.ncbi.nlm.nih.gov/pubmed/28358340
http://dx.doi.org/10.3390/molecules22040562
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