Pro-Angiogenic Effects of Low Dose Ethoxidine in a Murine Model of Ischemic Hindlimb: Correlation between Ethoxidine Levels and Increased Activation of the Nitric Oxide Pathway

Ethoxidine, a benzo[c]phenanthridine derivative, has been identified as a potent inhibitor of topoisomerase I in cancer cell lines. Our group has reported paradoxical properties of ethoxidine in cellular processes leading to angiogenesis on endothelial cells. Because low concentration ethoxidine is...

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Detalles Bibliográficos
Autores principales: Clere, Nicolas, To, Kim Hung Thien, Legeay, Samuel, Bertrand, Samuel, Helesbeux, Jean Jacques, Duval, Olivier, Faure, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154657/
https://www.ncbi.nlm.nih.gov/pubmed/28417947
http://dx.doi.org/10.3390/molecules22040627

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