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AlCl(3)·6H(2)O-Catalyzed Friedel-Crafts Alkylation of Indoles by the para-Quinone Methide Moiety of Celastrol

A classical Friedel-Crafts alkylation of different indoles catalyzed by AlCl(3)·6H(2)O has been developed for a well-known important natural product, celastrol, resulting in a series of derivatives for further biological evaluation. The catalyst loading was reduced to 5 mol %, the reaction proceeds...

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Detalles Bibliográficos
Autores principales:	Zhu, Yi, Chen, Ziwen, Huang, Zhenfei, Yan, Siwei, Li, Zhuoer, Zhou, Hu, Zhang, Xiaokun, Su, Ying, Zeng, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154665/ https://www.ncbi.nlm.nih.gov/pubmed/28509859 http://dx.doi.org/10.3390/molecules22050742

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