PPARγ agonist-loaded PLGA-PEG nanocarriers as a potential treatment for Alzheimer’s disease: in vitro and in vivo studies

OBJECTIVE: The first aim of this study was to develop a nanocarrier that could transport the peroxisome proliferator-activated receptor agonist, pioglitazone (PGZ) across brain endothelium and examine the mechanism of nanoparticle transcytosis. The second aim was to determine whether these nanocarri...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva-Abreu, Marcelle, Calpena, Ana Cristina, Andrés-Benito, Pol, Aso, Ester, Romero, Ignacio A, Roig-Carles, David, Gromnicova, Radka, Espina, Marta, Ferrer, Isidre, García, María Luisa, Male, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154713/
https://www.ncbi.nlm.nih.gov/pubmed/30271148
http://dx.doi.org/10.2147/IJN.S171490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154713/
https://www.ncbi.nlm.nih.gov/pubmed/30271148
http://dx.doi.org/10.2147/IJN.S171490

Ejemplares similares