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Modulation of genomic and epigenetic end-points by celecoxib
Celecoxib, a nonsteroidal anti-inflammatory drug that selectively targets cyclooxygenase-2, is a promising cancer chemopreventive agent. However, safety concerns have been raised in clinical trials evaluating its ability to prevent colorectal adenomas. The rationale for the herein reported studies w...
Autores principales: | Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna T., Pulliero, Alessandra, Geretto, Marta, Balansky, Roumen, De Flora, Silvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154745/ https://www.ncbi.nlm.nih.gov/pubmed/30263093 http://dx.doi.org/10.18632/oncotarget.26062 |
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