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Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

BACKGROUND: Circadian rhythms are fundamental to health and are particularly important for mental wellbeing. Disrupted rhythms of rest and activity are recognised as risk factors for major depressive disorder and bipolar disorder. METHODS: We conducted a genome-wide association study (GWAS) of low r...

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Detalles Bibliográficos
Autores principales: Ferguson, Amy, Lyall, Laura M., Ward, Joey, Strawbridge, Rona J., Cullen, Breda, Graham, Nicholas, Niedzwiedz, Claire L., Johnston, Keira J.A., MacKay, Daniel, Biello, Stephany M., Pell, Jill P., Cavanagh, Jonathan, McIntosh, Andrew M., Doherty, Aiden, Bailey, Mark E.S., Lyall, Donald M., Wyse, Cathy A., Smith, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154782/
https://www.ncbi.nlm.nih.gov/pubmed/30120083
http://dx.doi.org/10.1016/j.ebiom.2018.08.004