αβ T Cell Receptor Mechanosensing Forces out Serial Engagement

T lymphocytes use αβ T cell receptors (TCRs) to recognize sparse antigenic peptides bound to MHC molecules (pMHCs) arrayed on antigen-presenting cells (APCs). Contrary to conventional receptor–ligand associations exemplified by antigen-antibody interactions, forces play a crucial role in nonequilibr...

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Detalles Bibliográficos
Autores principales: Feng, Yinnian, Reinherz, Ellis L., Lang, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154790/
https://www.ncbi.nlm.nih.gov/pubmed/30060805
http://dx.doi.org/10.1016/j.it.2018.05.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154790/
https://www.ncbi.nlm.nih.gov/pubmed/30060805
http://dx.doi.org/10.1016/j.it.2018.05.005

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