Cargando…

αβ T Cell Receptor Mechanosensing Forces out Serial Engagement

T lymphocytes use αβ T cell receptors (TCRs) to recognize sparse antigenic peptides bound to MHC molecules (pMHCs) arrayed on antigen-presenting cells (APCs). Contrary to conventional receptor–ligand associations exemplified by antigen-antibody interactions, forces play a crucial role in nonequilibr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Yinnian, Reinherz, Ellis L., Lang, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154790/ https://www.ncbi.nlm.nih.gov/pubmed/30060805 http://dx.doi.org/10.1016/j.it.2018.05.005

Ejemplares similares

Harnessing αβ T cell receptor mechanobiology to achieve the promise of immuno-oncology
por: Reinherz, Ellis L., et al.
Publicado: (2023)

Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination
por: Brazin, Kristine N., et al.
Publicado: (2015)

Revisiting the Discovery of the αβ TCR Complex and Its Co-Receptors
por: Reinherz, Ellis L.
Publicado: (2014)

Single Molecule Force Spectroscopy Reveals Distinctions in Key Biophysical Parameters of αβ T-Cell Receptors Compared with Chimeric Antigen Receptors Directed at the Same Ligand
por: Banik, Debasis, et al.
Publicado: (2021)

Mechanosensing, from forces to structures
por: Zhao, Feng, et al.
Publicado: (2022)

Asymmetric framework motion of TCRαβ controls load-dependent peptide discrimination
por: Chang-Gonzalez, Ana C., et al.
Publicado: (2023)

Receptor-mediated cell mechanosensing
por: Chen, Yunfeng, et al.
Publicado: (2017)

Molecular design of the γδT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing
por: Mallis, Robert J., et al.
Publicado: (2021)

Genesis of the αβ T-cell receptor
por: Dupic, Thomas, et al.
Publicado: (2019)

Actomyosin meshwork mechanosensing enables tissue shape to orient cell force
por: Chanet, Soline, et al.
Publicado: (2017)

Editorial: From mechanosensing to signalling and cell response: The ion channel force
por: Gkika, Dimitra, et al.
Publicado: (2023)

Strict Major Histocompatibility Complex Molecule Class-Specific Binding by Co-Receptors Enforces MHC-Restricted αβ TCR Recognition during T Lineage Subset Commitment
por: Li, Xiao-Long, et al.
Publicado: (2013)

αβ T cell receptors as predictors of health and disease
por: Attaf, Meriem, et al.
Publicado: (2015)

Mechanosensing by Gli1(+) cells contributes to the orthodontic force‐induced bone remodelling
por: Liu, An‐Qi, et al.
Publicado: (2020)

Expression of The αβ T-Cell Receptor Is Necessary for The Generation of The Thymic Medulla
por: Palmer, Donald B., et al.
Publicado: (1993)

The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening
por: Andreu, Ion, et al.
Publicado: (2021)

Cooperative motility, force generation and mechanosensing in a foraging non-photosynthetic diatom
por: Zheng, Peng, et al.
Publicado: (2023)

Platelet Mechanosensing of Collagen Matrices
por: Kee, Matthew F., et al.
Publicado: (2015)

Three-Dimensional Quantification of Cellular Traction Forces and Mechanosensing of Thin Substrata by Fourier Traction Force Microscopy
por: del Álamo, Juan C., et al.
Publicado: (2013)

Genetics of Mechanosensation in the Heart
por: Buyandelger, Byambajav, et al.
Publicado: (2011)

The role of lipids in mechanosensation
por: Pliotas, Christos, et al.
Publicado: (2015)

Mechanosensation in leaf veins
por: Yang, Tsu-Hao, et al.
Publicado: (2023)

Nucleus Mechanosensing in Cardiomyocytes
por: Coscarella, Isabella Leite, et al.
Publicado: (2023)

Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair
por: Zhou, Dennis W., et al.
Publicado: (2021)

Mechanosensing and Regulation of Cardiac Function
por: Dostal, David E, et al.
Publicado: (2014)

Mechanosensation and Mechanotransduction in Natural Killer Cells
por: Santoni, Giorgio, et al.
Publicado: (2021)

Nuclear Mechanosensation and Mechanotransduction in Vascular Cells
por: Salvador, Jocelynda, et al.
Publicado: (2022)

A Molecular Docking Study Reveals That Short Peptides Induce Conformational Changes in the Structure of Human Tubulin Isotypes αβI, αβII, αβIII and αβIV
por: Ebenezer, Oluwakemi, et al.
Publicado: (2023)

Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes
por: Gon, Stéphanie, et al.
Publicado: (2018)

Collective Cell Behavior in Mechanosensing of Substrate Thickness
por: Tusan, Camelia G., et al.
Publicado: (2018)

The transcriptional landscape of αβ T cell differentiation
por: Mingueneau, Michael, et al.
Publicado: (2013)

Synergy between the pre–T cell receptor and Notch: cementing the αβ lineage choice
por: Guidos, Cynthia J.
Publicado: (2006)

Biomechanics of vascular mechanosensation and remodeling
por: Baeyens, Nicolas, et al.
Publicado: (2016)

Molecular Mechanisms of Cellular Mechanosensing
por: Luo, Tianzhi, et al.
Publicado: (2013)

Force Generation upon T Cell Receptor Engagement
por: Husson, Julien, et al.
Publicado: (2011)

Glial Tissue Mechanics and Mechanosensing by Glial Cells
por: Pogoda, Katarzyna, et al.
Publicado: (2018)

Cell mechanosensing underlies homeostasis of multicellular systems
por: Nonomura, Keiko, et al.
Publicado: (2020)

Mechanosensing of Mechanical Confinement by Mesenchymal-Like Cells
por: Doolin, Mary T., et al.
Publicado: (2020)

The ‘Yin and Yang’ of Cancer Cell Growth and Mechanosensing
por: Amer, Malak, et al.
Publicado: (2021)

A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans
por: Edwards, Sarah C., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2b7r3b83i5g3ll4dvsqq3uvpiq