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Give me a SINE: how Selective Inhibitors of Nuclear Export modulate autophagy and aging
Autophagy is a cellular recycling process leading to lysosomal degradation of damaged macromolecules, which can protect cells against aging. The transcription factor EB (TFEB), a major transcriptional regulator of genes involved in autophagy and lysosomal function, is emerging as an attractive targe...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154834/ https://www.ncbi.nlm.nih.gov/pubmed/30263946 http://dx.doi.org/10.1080/23723556.2018.1502511 |