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Give me a SINE: how Selective Inhibitors of Nuclear Export modulate autophagy and aging

Autophagy is a cellular recycling process leading to lysosomal degradation of damaged macromolecules, which can protect cells against aging. The transcription factor EB (TFEB), a major transcriptional regulator of genes involved in autophagy and lysosomal function, is emerging as an attractive targe...

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Detalles Bibliográficos
Autores principales:	Kumar, A.V., Thakurta, T.G., Silvestrini, M.J., Johnson, J.R., Reenan, R.A., Lapierre, L.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154834/ https://www.ncbi.nlm.nih.gov/pubmed/30263946 http://dx.doi.org/10.1080/23723556.2018.1502511

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