DNA repair synthesis and histone deposition partner during homologous recombination

Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chrom...

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Detalles Bibliográficos
Autores principales: Elbakry, Amira, Juhász, Szilvia, Mathes, Arthur, Löbrich, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154852/
https://www.ncbi.nlm.nih.gov/pubmed/30263950
http://dx.doi.org/10.1080/23723556.2018.1511210
Descripción
Sumario:Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chromatin remodeling complex regulates DNA repair synthesis during homologous recombination.

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