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Cdk6: At the interface of Rb and p53

In cancer the activity of cyclin-dependent kinase 4-(CDK4) and cyclin-dependent kinase 6 (CDK6)-cyclin complexes are frequently altered with enhanced CDK6 expression found in hematopoietic malignancies. Our latest findings show a so far unknown role of Cdk6 during oncogene-induced stress and transfo...

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Detalles Bibliográficos
Autores principales: Nebenfuehr, Sofie, Bellutti, Florian, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154857/
https://www.ncbi.nlm.nih.gov/pubmed/30263948
http://dx.doi.org/10.1080/23723556.2018.1511206