Comparative single-dose pharmacokinetics of sildenafil after oral and rectal administration in healthy beagle dogs

BACKGROUND: Sildenafil citrate, a highly selective phosphodiesterase type 5 inhibitor, is used to treat pulmonary hypertension (PH) in veterinary medicine. The objective of this study was to investigate pharmacokinetic profiles by oral administration of orally disintegrating film (ODF) and film coat...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hyuck-Joo, Oh, Ye-In, Jeong, Jong-Woo, Song, Kun-Ho, Koo, Tae-Sung, Seo, Kyoung-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154896/
https://www.ncbi.nlm.nih.gov/pubmed/30249242
http://dx.doi.org/10.1186/s12917-018-1617-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154896/
https://www.ncbi.nlm.nih.gov/pubmed/30249242
http://dx.doi.org/10.1186/s12917-018-1617-7

Ejemplares similares