Alzheimer’s associated amyloid and tau deposition co-localizes with a homeostatic myelin repair pathway in two mouse models of post-stroke mixed dementia

The goal of this study was to determine the chronic impact of stroke on the manifestation of Alzheimer’s disease (AD) related pathology and behavioral impairments in mice. To accomplish this goal, we used two distinct models. First, we experimentally induced ischemic stroke in aged wildtype (wt) C57...

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Detalles Bibliográficos
Autores principales: Nguyen, Thuy-Vi V., Hayes, Megan, Zbesko, Jacob C., Frye, Jennifer B., Congrove, Nicole R., Belichenko, Nadia P., McKay, Brian S., Longo, Frank M., Doyle, Kristian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154927/
https://www.ncbi.nlm.nih.gov/pubmed/30249297
http://dx.doi.org/10.1186/s40478-018-0603-4

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