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Heme-dependent Inactivation of 5-Aminolevulinate Synthase from Caulobacter crescentus
The biosynthesis of heme is strictly regulated, probably because of the toxic effects of excess heme and its biosynthetic precursors. In many organisms, heme biosynthesis starts with the production of 5-aminolevulinic acid (ALA) from glycine and succinyl-coenzyme A, a process catalyzed by a homodime...
Autores principales: | Ikushiro, Hiroko, Nagami, Atsushi, Takai, Tomoko, Sawai, Taiki, Shimeno, Yuki, Hori, Hiroshi, Miyahara, Ikuko, Kamiya, Nobuo, Yano, Takato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154995/ https://www.ncbi.nlm.nih.gov/pubmed/30242198 http://dx.doi.org/10.1038/s41598-018-32591-z |
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