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Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway

The molecular mechanisms underlying the metabolic shift toward increased glycolysis observed in pulmonary artery smooth muscle cells (PASMC) during the pathogenesis of pulmonary arterial hypertension (PAH) are not fully understood. Here we show that the glycolytic enzyme α-enolase (ENO1) regulates t...

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Detalles Bibliográficos
Autores principales:	Dai, Jingbo, Zhou, Qiyuan, Chen, Jiwang, Rexius-Hall, Megan L., Rehman, Jalees, Zhou, Guofei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155017/ https://www.ncbi.nlm.nih.gov/pubmed/30242159 http://dx.doi.org/10.1038/s41467-018-06376-x

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