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Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket
Epilepsy has been treated for centuries with herbal remedies, including leaves of the African shrub Mallotus oppositifolius, yet the underlying molecular mechanisms have remained unclear. Voltage-gated potassium channel isoforms KCNQ2–5, predominantly KCNQ2/3 heteromers, underlie the neuronal M-curr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155021/ https://www.ncbi.nlm.nih.gov/pubmed/30242262 http://dx.doi.org/10.1038/s41467-018-06339-2 |