Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

The insulin/insulin-like growth factor signalling axis is an evolutionary ancient and highly conserved hormonal system involved in the regulation of metabolism, growth and lifespan in animals. Human insulin is stored in the pancreas, while insulin-like growth factor-1 (IGF-1) is maintained in blood...

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Detalles Bibliográficos
Autores principales: Roed, Nikolaj Kulahin, Viola, Cristina M., Kristensen, Ole, Schluckebier, Gerd, Norrman, Mathias, Sajid, Waseem, Wade, John D., Andersen, Asser Sloth, Kristensen, Claus, Ganderton, Timothy R., Turkenburg, Johan P., De Meyts, Pierre, Brzozowski, Andrzej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155051/
https://www.ncbi.nlm.nih.gov/pubmed/30242155
http://dx.doi.org/10.1038/s41467-018-06192-3

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