Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force

LmrA is a bacterial ATP-binding cassette (ABC) multidrug exporter that uses metabolic energy to transport ions, cytotoxic drugs, and lipids. Voltage clamping in a Port-a-Patch was used to monitor electrical currents associated with the transport of monovalent cationic HEPES(+) by single-LmrA transpo...

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Detalles Bibliográficos
Autores principales: Agboh, Kelvin, Lau, Calvin H. F., Khoo, Yvonne S. K., Singh, Himansha, Raturi, Sagar, Nair, Asha V., Howard, Julie, Chiapello, Marco, Feret, Renata, Deery, Michael J., Murakami, Satoshi, van Veen, Hendrik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155054/
https://www.ncbi.nlm.nih.gov/pubmed/30255140
http://dx.doi.org/10.1126/sciadv.aas9365

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