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Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

Efficient chromophore supply is paramount for the continuous function of vertebrate cone photoreceptors. It is well established that isomerization of all-trans- to 11-cis- retinoid in the retinal pigmented epithelium by RPE65 is a key reaction in this process. Mutations in RPE65 result in a disrupte...

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Detalles Bibliográficos
Autores principales: Kolesnikov, Alexander V., Tang, Peter H., Kefalov, Vladimir J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155087/
https://www.ncbi.nlm.nih.gov/pubmed/30242264
http://dx.doi.org/10.1038/s41598-018-32667-w

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