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BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis

Transcription factor (TF) networks determine cell fate in hematopoiesis. However, how TFs cooperate with other regulatory mechanisms to instruct transcription remains poorly understood. Here we show that in small pre-B cells, the lineage restricted epigenetic reader BRWD1 closes early development en...

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Detalles Bibliográficos
Autores principales: Mandal, Malay, Maienschein-Cline, Mark, Maffucci, Patrick, Veselits, Margaret, Kennedy, Domenick E., McLean, Kaitlin C., Okoreeh, Michael K., Karki, Sophiya, Cunningham-Rundles, Charlotte, Clark, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155124/
https://www.ncbi.nlm.nih.gov/pubmed/30250168
http://dx.doi.org/10.1038/s41467-018-06165-6