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Three-Component Reaction of Benzylamines, Diethyl Phosphite and Triethyl Orthoformate: Dependence of the Reaction Course on the Structural Features of the Substrates and Reaction Conditions

The reaction between benzyl amines, triethyl orthoformate, and diethyl phosphite affords either bisphosphonic (compound 1) or N-benzylaminobenzylphosphonic (compound 2) acid depending on the reaction conditions. The final output of the reaction can be manipulated by the choice of reaction conditions...

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Detalles Bibliográficos
Autores principales: Miszczyk, Patrycja, Turowska-Tyrk, Ilona, Kafarski, Paweł, Chmielewska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155184/
https://www.ncbi.nlm.nih.gov/pubmed/28287472
http://dx.doi.org/10.3390/molecules22030450