Cargando…

Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties

Thirty six novel heterocyclic derivatives of ethyl 2-(2-pyridylacetate) were efficiently synthesized. The new compounds involve the linkage of a 2-pyridyl ring with thiosemicarbazide (compounds 1–7), 1,2,4-triazole (compounds 1a–7a), 1,3,4-thiadiazole (compounds 1b–7b), and 1,3,4-oxadiazole (compoun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szulczyk, Daniel, Tomaszewski, Piotr, Jóźwiak, Michał, Kozioł, Anna E., Lis, Tadeusz, Collu, David, Iuliano, Filippo, Struga, Marta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155191/ https://www.ncbi.nlm.nih.gov/pubmed/28272311 http://dx.doi.org/10.3390/molecules22030409

Ejemplares similares

Synthesis, Structural Studies and Biological Evaluation of Connections of Thiosemicarbazide, 1,2,4-Triazole and 1,3,4-Thiadiazole with Palmitic Acid
por: Jóźwiak, Michał, et al.
Publicado: (2018)

Synthesis and Biological Activity of Substituted Urea and Thiourea Derivatives Containing 1,2,4-Triazole Moieties
por: Kocyigit-Kaymakcioglu, Bedia, et al.
Publicado: (2013)

Synthesis and Biological Evaluation of Novel Indole-Derived Thioureas
por: Sanna, Giuseppina, et al.
Publicado: (2018)

Decarboxylative trifluoromethylthiolation of pyridylacetates
por: Kawanishi, Ryouta, et al.
Publicado: (2021)

Synthesis of Oxadiazoles, Thiadiazoles and Triazoles Derived from Benzo[b]thiophene.
por: Sharba, A. Hussain K., et al.
Publicado: (2005)

Synthesis and Biological Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Containing a Phenylalanine Moiety
por: Moise, Mihaela, et al.
Publicado: (2009)

Synthesis of new, highly luminescent bis(2,2’-bithiophen-5-yl) substituted 1,3,4-oxadiazole, 1,3,4-thiadiazole and 1,2,4-triazole
por: Kostyuchenko, Anastasia S, et al.
Publicado: (2014)

Synthesis of Thiadiazoles and 1,2,4-Triazoles Derived from Cyclopropane Dicarboxylic Acid .
por: Sharba, A. Hussain K., et al.
Publicado: (2005)

Synthesis of Novel 2,5-Disubstituted-1,3,4-thiadiazoles Clubbed 1,2,4-Triazole, 1,3,4-Thiadiazole, 1,3,4-Oxadiazole and/or Schiff Base as Potential Antimicrobial and Antiproliferative Agents
por: Rezki, Nadjet, et al.
Publicado: (2015)

Microwave Assisted Synthesis, Antifungal Activity and DFT Theoretical Study of Some Novel 1,2,4-Triazole Derivatives Containing the 1,2,3-Thiadiazole Moiety
por: Sun, Na-Bo, et al.
Publicado: (2013)

Synthesis and Antibacterial Evaluation of New Sulfone Derivatives Containing 2-Aroxymethyl-1,3,4-Oxadiazole/Thiadiazole Moiety
por: Su, Shihu, et al.
Publicado: (2016)

Boosting the Energetic Performance of Trinitromethyl-1,2,4-oxadiazole Moiety by Increasing Nitrogen-Oxygen in the Bridge
por: Chen, Peng, et al.
Publicado: (2022)

Design, Synthesis, and Biological Activity of Novel Chalcone Derivatives Containing an 1,2,4-Oxadiazole Moiety
por: Luo, Ling, et al.
Publicado: (2022)

Synthesis and Biological Properties of Novel Triazole-Thiol and Thiadiazole Derivatives of the 1,2,4-Triazole-3(5)-one Class
por: Düğdü, Esra, et al.
Publicado: (2014)

Design, Synthesis, and Biological Evaluation of 1,2,4-Thiadiazole-1,2,4-Triazole Derivatives Bearing Amide Functionality as Anticancer Agents
por: Pragathi, Yazala Jyothsna, et al.
Publicado: (2020)

Biological activity of oxadiazole and thiadiazole derivatives
por: Atmaram, Upare Abhay, et al.
Publicado: (2022)

4-(3-Fluorophenyl)-1-(propan-2-ylidene)thiosemicarbazone
por: Miroslaw, Barbara, et al.
Publicado: (2011)

Synthesis and Evaluation of New Oxadiazole, Thiadiazole, and Triazole Derivatives as Potential Anticancer Agents Targeting MMP-9
por: Özdemir, Ahmet, et al.
Publicado: (2017)

N-Carbethoxy-N′-(3-phenyl-1H-1,2,4-triazol-5-yl)thiourea
por: Dolzhenko, Anton V., et al.
Publicado: (2010)

Synthesis and Crystal Structure of Novel Sulfone Derivatives Containing 1,2,4-Triazole Moieties
por: Xu, Weiming, et al.
Publicado: (2010)

Synthesis and antimicrobial evaluation of some novel 1,2,4-triazole and 1,3,4-thiadiazole derivatives
por: Popiołek, Łukasz, et al.
Publicado: (2012)

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety
por: Abdelriheem, Nadia A., et al.
Publicado: (2017)

Synthesis and Cytotoxicity Evaluation of Some Novel Thiazoles, Thiadiazoles, and Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones Incorporating Triazole Moiety
por: Gomha, Sobhi M., et al.
Publicado: (2015)

N-Carbethoxy-N′-[3-(4-methylphenyl)-1H-1,2,4-triazol-5-yl]thiourea
por: Dolzhenko, Anton V., et al.
Publicado: (2010)

Evaluation of Biological Activity of New 1,2,4-Triazole Derivatives Containing Propionic Acid Moiety
por: Paprocka, Renata, et al.
Publicado: (2023)

Synthesis of Oxadiazole-Thiadiazole Hybrids and Their Anticandidal Activity
por: Levent, Serkan, et al.
Publicado: (2017)

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles
por: Moiola, Mattia, et al.
Publicado: (2020)

2-(1,2,4-triazole-5-yl)-1,3,4-oxadiazole as a novel building block for energetic materials
por: Dong, Zheting, et al.
Publicado: (2022)

Synthesis and Screening of New [1,3,4]Oxadiazole, [1,2,4]Triazole, and [1,2,4]Triazolo[4,3-b][1,2,4]triazole Derivatives as Potential Antitumor Agents on the Colon Carcinoma Cell Line (HCT-116)
por: Abdelrehim, El-sayed M.
Publicado: (2021)

Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors
por: Jin, Xiao-Yan, et al.
Publicado: (2019)

Synthesis of new Schiff bases bearing 1,2,4-triazole, thiazolidine and chloroazetidine moieties and their pharmacological evaluation
por: Kandile, Nadia G., et al.
Publicado: (2016)

Synthesis and Antiproliferative Evaluation of Novel Longifolene-Derived Tetralone Derivatives Bearing 1,2,4-Triazole Moiety
por: Zhu, Xia-Ping, et al.
Publicado: (2020)

Synthesis, analgesic and anti-inflammatory activities of new methyl-imidazolyl-1,3,4-oxadiazoles and 1,2,4-triazoles
por: Almasirad, Ali, et al.
Publicado: (2014)

Synthesis and characterization of novel bioactive 1,2,4-oxadiazole natural product analogs bearing the N-phenylmaleimide and N-phenylsuccinimide moieties
por: Maftei, Catalin V, et al.
Publicado: (2013)

Synthetic Transition from Thiourea-Based Compounds to Tetrazole Derivatives: Structure and Biological Evaluation of Synthesized New N-(Furan-2-ylmethyl)-1H-tetrazol-5-amine Derivatives
por: Szulczyk, Daniel, et al.
Publicado: (2021)

Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery
por: Biernacki, Karol, et al.
Publicado: (2020)

Room Temperature Synthesis of Bioactive 1,2,4-Oxadiazoles †
por: Baykov, Sergey V., et al.
Publicado: (2023)

Synthesis and Antimicrobial Activity of New 5-(2-Thienyl)-1,2,4-triazoles and 5-(2-Thienyl)-1,3,4-oxadiazoles and Related Derivatives
por: Al-Omar, Mohamed A.
Publicado: (2010)

Dataset on theoretical bio-evaluation of 1,2,4-thiadiazole-1,2,4-triazole analogues against epidermal growth factor receptor kinase down regulating human lung cancer
por: Oyebamiji, Abel Kolawole, et al.
Publicado: (2021)

Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide
por: Hassanzadeh, Farshid, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2m12hlu89rmm33k3er4fd21jdf