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POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling

Copy number variations (CNVs) are key drivers of colorectal cancer (CRC). Our previous studies revealed that protein O-fucosyltransferase 1 (POFUT1) overexpression is driven by CNVs during CRC development. The potential role and underlying mechanisms of POFUT1 in CRC were not investigated. In this s...

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Detalles Bibliográficos
Autores principales:	Du, Yuheng, Li, Daojiang, Li, Nanpeng, Su, Chen, Yang, Chunxing, Lin, Changwei, Chen, Miao, Wu, Runliu, Li, Xiaorong, Hu, Gui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155199/ https://www.ncbi.nlm.nih.gov/pubmed/30250219 http://dx.doi.org/10.1038/s41419-018-1055-2

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