Nod2 Deficiency in mice is Associated with Microbiota Variation Favouring the Expansion of mucosal CD4+ LAP+ Regulatory Cells

Nucleotide-binding Oligomerization Domain-2 (NOD2) mutations are associated with an increased risk to develop Crohn’s Disease. In previous studies, we have shown that Nod2−/− mice manifest increased proportion of Lamina Propria (LP) CD4+ LAP+ Foxp3− regulatory cells, when compared with Nod2+/+ mice,...

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Detalles Bibliográficos
Autores principales: Butera, A., Di Paola, M., Pavarini, L., Strati, F., Pindo, M., Sanchez, M., Cavalieri, D., Boirivant, M., De Filippo, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155205/
https://www.ncbi.nlm.nih.gov/pubmed/30250234
http://dx.doi.org/10.1038/s41598-018-32583-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155205/
https://www.ncbi.nlm.nih.gov/pubmed/30250234
http://dx.doi.org/10.1038/s41598-018-32583-z

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