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A UPLC-MS/MS Method for Simultaneous Determination of Free and Total Forms of a Phenolic Acid and Two Flavonoids in Rat Plasma and Its Application to Comparative Pharmacokinetic Studies of Polygonum capitatum Extract in Rats
The principal active constituents of Polygonum capitatum are phenolic acids and flavonoids, such as gallic acid, quercitrin, and quercetin. The aim of this study was to develop and validate a method to determine the three constituents and the corresponding conjugated metabolites of Polygonum capitat...
Autores principales: | Huang, Yong, Sun, Hui-Yuan, Qin, Xiao-Li, Li, Yong-Jun, Liao, Shang-Gao, Gong, Zi-Peng, Lu, Yuan, Wang, Yong-Lin, Wang, Ai-Min, Lan, Yan-Yu, Zheng, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155221/ https://www.ncbi.nlm.nih.gov/pubmed/28245598 http://dx.doi.org/10.3390/molecules22030353 |
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