Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles

Based on consecutive one-pot conditions combining three palladium-catalyzed reactions (Sonogashira, Heck and Suzuki-Miyaura reactions), a more efficient domino multicomponent method has been successfully developed to access a wide variety of 3-(diarylmethylene)oxindoles. Microwave irradiation and us...

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Autores principales: Park, Sunhwa, Lee, Jiyun, Shin, Kye Jung, Oh, Euichaul, Seo, Jae Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155274/
https://www.ncbi.nlm.nih.gov/pubmed/28327536
http://dx.doi.org/10.3390/molecules22030503
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author Park, Sunhwa
Lee, Jiyun
Shin, Kye Jung
Oh, Euichaul
Seo, Jae Hong
author_facet Park, Sunhwa
Lee, Jiyun
Shin, Kye Jung
Oh, Euichaul
Seo, Jae Hong
author_sort Park, Sunhwa
collection PubMed
description Based on consecutive one-pot conditions combining three palladium-catalyzed reactions (Sonogashira, Heck and Suzuki-Miyaura reactions), a more efficient domino multicomponent method has been successfully developed to access a wide variety of 3-(diarylmethylene)oxindoles. Microwave irradiation and use of a silver salt were the most important factors to achieve high yields and stereoselectivity.
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spelling pubmed-61552742018-11-13 Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles Park, Sunhwa Lee, Jiyun Shin, Kye Jung Oh, Euichaul Seo, Jae Hong Molecules Article Based on consecutive one-pot conditions combining three palladium-catalyzed reactions (Sonogashira, Heck and Suzuki-Miyaura reactions), a more efficient domino multicomponent method has been successfully developed to access a wide variety of 3-(diarylmethylene)oxindoles. Microwave irradiation and use of a silver salt were the most important factors to achieve high yields and stereoselectivity. MDPI 2017-03-22 /pmc/articles/PMC6155274/ /pubmed/28327536 http://dx.doi.org/10.3390/molecules22030503 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Sunhwa
Lee, Jiyun
Shin, Kye Jung
Oh, Euichaul
Seo, Jae Hong
Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title_full Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title_fullStr Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title_full_unstemmed Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title_short Consecutive One-Pot versus Domino Multicomponent Approaches to 3-(Diarylmethylene)oxindoles
title_sort consecutive one-pot versus domino multicomponent approaches to 3-(diarylmethylene)oxindoles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155274/
https://www.ncbi.nlm.nih.gov/pubmed/28327536
http://dx.doi.org/10.3390/molecules22030503
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AT oheuichaul consecutiveonepotversusdominomulticomponentapproachesto3diarylmethyleneoxindoles
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