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Reversible Human Immunodeficiency Virus Type-1 Latency in Primary Human Monocyte-Derived Macrophages Induced by Sustained M1 Polarization

We have reported that short-term stimulation of primary human monocyte-derived macrophages (MDM) with interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α), i.e. M1 polarization, leads to a significant containment of virus replication. Here we show that M1-MDM restimulation with these cytokines 7...

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Detalles Bibliográficos
Autores principales: Graziano, Francesca, Aimola, Giulia, Forlani, Greta, Turrini, Filippo, Accolla, Roberto S., Vicenzi, Elisa, Poli, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155284/
https://www.ncbi.nlm.nih.gov/pubmed/30250078
http://dx.doi.org/10.1038/s41598-018-32451-w

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