Cargando…

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents in HepG-2 Cell Line

Cancer is a major public health concern worldwide. Adverse effects of cancer treatments still compromise patients’ quality of life. To identify new potential anticancer agents, a series of novel pyrazoline derivatives were synthesized and evaluated for cytotoxic effects on HepG-2 (human liver hepato...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Weijie, Pan, Ying, Wang, Hong, Li, Haiyan, Peng, Qing, Wei, Duncan, Chen, Cheng, Zheng, Jinhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155299/ https://www.ncbi.nlm.nih.gov/pubmed/28300751 http://dx.doi.org/10.3390/molecules22030467

Ejemplares similares

A New Series of Cytotoxic Pyrazoline Derivatives as Potential Anticancer Agents that Induce Cell Cycle Arrest and Apoptosis
por: Wang, Hong, et al.
Publicado: (2017)

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
por: Karabacak, Muhammed, et al.
Publicado: (2015)

Synthesis, Anticancer Assessment, and Molecular Docking of Novel Chalcone-Thienopyrimidine Derivatives in HepG2 and MCF-7 Cell Lines
por: Safwat, Ghada M., et al.
Publicado: (2021)

Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview
por: Matiadis, Dimitris, et al.
Publicado: (2020)

Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents
por: Moreno, Leydi M., et al.
Publicado: (2018)

Anticancer Effect of Rh2, a Histone Deacetylase Inhibitor, in HepG2 Cells and HepG2 Cell-Derived Xenograft Tumors Occurs via the Inhibition of HDACs and Activation of the MAPK Signaling Pathway
por: Qiang, Shi Qing, et al.
Publicado: (2021)

Pyrazoline derivatives as promising novel antischistosomal agents
por: Morais, Cristiane S., et al.
Publicado: (2021)

Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis
por: Zhou, Rui-sheng, et al.
Publicado: (2019)

Cytotoxicity and genotoxicity of stilbene derivatives in CHO-K1 and HepG2 cell lines
por: Mizuno, Cassia Suemi, et al.
Publicado: (2017)

Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents
por: Kumari, Priti, et al.
Publicado: (2020)

Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells
por: Al-Warhi, Tarfah, et al.
Publicado: (2022)

Characterization of dengue virus entry into HepG2 cells
por: Suksanpaisan, Lukkana, et al.
Publicado: (2009)

Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis and Autophagy
por: Miao, Qing, et al.
Publicado: (2013)

Lipid synthesis and secretion in HepG2 cells is not affected by ACTH
por: Skoog, Maria, et al.
Publicado: (2010)

Nevirapine induced mitochondrial dysfunction in HepG2 cells
por: Paemanee, Atchara, et al.
Publicado: (2017)

Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells
por: Jiang, Qin, et al.
Publicado: (2017)

Influence of limonin on Wnt signalling molecule in HepG2 cell lines
por: Langeswaran, K., et al.
Publicado: (2013)

The Curious Case of the HepG2 Cell Line: 40 Years of Expertise
por: Arzumanian, Viktoriia A., et al.
Publicado: (2021)

Exploring Dynamic Metabolome of the HepG2 Cell Line: Rise and Fall
por: Kiseleva, Olga I., et al.
Publicado: (2022)

Comparison of various synthesis methods and synthesis parameters of pyrazoline derivates
por: Praceka, Meilinda Setya, et al.
Publicado: (2021)

Bio-Oriented Synthesis and Molecular Docking Studies of 1,2,4-Triazole Based Derivatives as Potential Anti-Cancer Agents against HepG2 Cell Line
por: Akhter, Naheed, et al.
Publicado: (2023)

The monoacylglycerol acyltransferase pathway contributes to triacylglycerol synthesis in HepG2 cells
por: McFie, Pamela J., et al.
Publicado: (2022)

Novel 2-Pyrazoline Derivatives as Potential Antibacterial and Antifungal Agents
por: Kini, Suvarna, et al.
Publicado: (2008)

Publisher Correction: Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents
por: Kumari, Priti, et al.
Publicado: (2020)

Antitumor effect and mechanism of an ellagic acid derivative on the HepG2 human hepatocellular carcinoma cell line
por: ZHANG, HUI, et al.
Publicado: (2014)

Synthesis, Characterization of Liposomes Modified with Biosurfactant MEL-A Loading Betulinic Acid and Its Anticancer Effect in HepG2 Cell
por: Shu, Qin, et al.
Publicado: (2019)

Optimization of Three Dimensional Culturing of the HepG2 Cell Line in Fibrin Scaffold
por: Banihashemi, Mehrzad, et al.
Publicado: (2015)

Haplotype-resolved and integrated genome analysis of the cancer cell line HepG2
por: Zhou, Bo, et al.
Publicado: (2019)

The effect of Moringa oleifera crude extract on liver cell line, HepG2
por: Sowunmi, Boluwatife O., et al.
Publicado: (2023)

Pyrazoles and Pyrazolines as Anti-Inflammatory Agents
por: Mantzanidou, Martha, et al.
Publicado: (2021)

Knockdown of nucleophosmin induces S-phase arrest in HepG2 cells
por: Wang, Qing-Qing, et al.
Publicado: (2011)

Artificial cells eavesdropping on HepG2 cells
por: Westensee, Isabella Nymann, et al.
Publicado: (2023)

Coumarin–carbazole based functionalized pyrazolines: synthesis, characterization, anticancer investigation and molecular docking
por: Patel, Mrugesh, et al.
Publicado: (2021)

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents
por: Edrees, Mastoura M., et al.
Publicado: (2018)

Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents
por: Moreno, Leydi M., et al.
Publicado: (2020)

In Vitro Anticancer Potential of Berberis lycium Royle Extracts against Human Hepatocarcinoma (HepG2) Cells
por: Mustafa, Kiren, et al.
Publicado: (2020)

Suaeda vermiculata Aqueous-Ethanolic Extract-Based Mitigation of CCl(4)-Induced Hepatotoxicity in Rats, and HepG-2 and HepG-2/ADR Cell-Lines-Based Cytotoxicity Evaluations
por: Mohammed, Salman A. A., et al.
Publicado: (2020)

Inhibition of phase-1 biotransformation and cytostatic effects of diphenyleneiodonium on hepatoblastoma cell line HepG2 and a CYP3A4-overexpressing HepG2 cell clone
por: Schulz, Christian, et al.
Publicado: (2021)

A New Approach to Synthesize of 4-Phenacylideneflavene Derivatives and to Evaluate Their Cytotoxic Effects on HepG2 Cell Line
por: Chen, Hongbin, et al.
Publicado: (2017)

Synthesis and characterization of some novel polythiophene derivatives containing pyrazoline
por: Trung, Vu Quoc, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_581p74rrjdds0m8p8i8j611n1l