2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β(3)-Adrenergic Activity

The β(3) adrenergic receptor is raising as an important drug target for the treatment of pathologies such as diabetes, obesity, depression, and cardiac diseases among others. Several attempts to obtain selective and high affinity ligands have been made. Currently, Mirabegron is the only available dr...

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Detalles Bibliográficos
Autores principales: Apablaza, Gastón, Montoya, Luisa, Morales-Verdejo, Cesar, Mellado, Marco, Cuellar, Mauricio, Lagos, Carlos F., Soto-Delgado, Jorge, Chung, Hery, Pessoa-Mahana, Carlos David, Mella, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155312/
https://www.ncbi.nlm.nih.gov/pubmed/28273884
http://dx.doi.org/10.3390/molecules22030404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155312/
https://www.ncbi.nlm.nih.gov/pubmed/28273884
http://dx.doi.org/10.3390/molecules22030404

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