Cargando…

Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma

Osteosarcoma (OS), the most common primary cancer of bone, exhibits a high propensity for local invasion and distant metastasis. This study sought to elucidate the role of S phase kinase-associated protein (Skp2) in osteosarcoma invasion and metastasis and to explore flavokawain A (FKA), a natural c...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yidan, Zvi, Yoav S., Batko, Brian, Zaphiros, Nikolas, O’Donnell, Edmond F., Wang, Jichuan, Sato, Kenji, Yang, Rui, Geller, David S., Koirala, Pratistha, Zhang, Wendong, Du, Xiuquan, Piperdi, Sajida, Liu, Yang, Zheng, Deyou, Roth, Michael, Gill, Jonathan, Zhang, Jinghang, Ren, Tingting, Gorlick, Richard, Zi, Xiaolin, Hoang, Bang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155331/
https://www.ncbi.nlm.nih.gov/pubmed/30250282
http://dx.doi.org/10.1038/s41598-018-32428-9