DL0410 Ameliorates Memory and Cognitive Impairments Induced by Scopolamine via Increasing Cholinergic Neurotransmission in Mice

Deficiency of the cholinergic system is thought to play a vital role in cognitive impairment of dementia. DL0410 was discovered as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinestease (BuChE), with potent efficiency in in-vitro experiments, but its in vivo effect on the cholinerg...

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Detalles Bibliográficos
Autores principales: Lian, Wenwen, Fang, Jiansong, Xu, Lvjie, Zhou, Wei, Kang, De, Xiong, Wandi, Jia, Hao, Liu, Ai-Lin, Du, Guan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155334/
https://www.ncbi.nlm.nih.gov/pubmed/28272324
http://dx.doi.org/10.3390/molecules22030410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155334/
https://www.ncbi.nlm.nih.gov/pubmed/28272324
http://dx.doi.org/10.3390/molecules22030410

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