Cargando…

AIMP3 depletion causes genome instability and loss of stemness in mouse embryonic stem cells

Aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (AIMP3) is a component of the multi-aminoacyl-tRNA synthetase complex and is involved in diverse cellular processes. Given that AIMP3 deficiency causes early embryonic lethality in mice, AIMP3 is expected to play a critical role in earl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Sun Mi, Jeon, Yoon, Kim, Doyeun, Jang, Hyonchol, Bae, June Sung, Park, Mi Kyung, Kim, Hongtae, Kim, Sunghoon, Lee, Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155375/ https://www.ncbi.nlm.nih.gov/pubmed/30250065 http://dx.doi.org/10.1038/s41419-018-1037-4

Ejemplares similares

AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice
por: Kim, Doyeun, et al.
Publicado: (2018)

Loss of Mob1a/b impairs the differentiation of mouse embryonic stem cells into the three germ layer lineages
por: Bae, June Sung, et al.
Publicado: (2019)

HIF1α‐mediated AIMP3 suppression delays stem cell aging via the induction of autophagy
por: Kim, Chul, et al.
Publicado: (2019)

AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis
por: Kim, Dae Gyu, et al.
Publicado: (2022)

Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli
por: Jha, Roshan, et al.
Publicado: (2017)

AIMp1 Potentiates T(H)1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity
por: Liang, Dan, et al.
Publicado: (2018)

Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug
por: Lee, BoRa, et al.
Publicado: (2022)

Anticancer Activity of Pyrimethamine via Ubiquitin Mediated Degradation of AIMP2-DX2
por: Kim, Dae Gyu, et al.
Publicado: (2020)

Single-cell analysis of AIMP2 splice variants informs on drug sensitivity and prognosis in hematologic cancer
por: Ku, Jayoung, et al.
Publicado: (2020)

The DRS–AIMP2–EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex
por: Hahn, Hyunggu, et al.
Publicado: (2019)

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
por: Yun, Seung Pil, et al.
Publicado: (2017)

Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells
por: Boo, Kyungjin, et al.
Publicado: (2015)

Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis
por: Choi, Jin Woo, et al.
Publicado: (2011)

Depletion of Janus kinase-2 promotes neuronal differentiation of mouse embryonic stem cells
por: Oh, Mihee, et al.
Publicado: (2021)

An Isoform of the Oncogenic Splice Variant AIMP2-DX2 Detected by a Novel Monoclonal Antibody
por: Kim, Dae Gyu, et al.
Publicado: (2020)

Ratio of Autoantibodies of Tumor Suppressor AIMP2 and Its Oncogenic Variant Is Associated with Clinical Outcome in Lung Cancer
por: Jung, Ji Ye, et al.
Publicado: (2017)

Parthanatos Mediates AIMP2 Activated Age Dependent Dopaminergic Neuronal Loss
por: Lee, Yunjong, et al.
Publicado: (2013)

Chromosome Instability in mouse Embryonic Stem Cells
por: Gaztelumendi, Nerea, et al.
Publicado: (2014)

Degradation of AIMP1/p43 Induced by Hepatitis C Virus E2 Leads to Upregulation of TGF-β Signaling and Increase in Surface Expression of gp96
por: Kim, Min Soo, et al.
Publicado: (2014)

Mapping the contact surfaces in the Lamin A:AIMP3 complex by hydrogen/deuterium exchange FT-ICR mass spectrometry
por: Tao, Yeqing, et al.
Publicado: (2017)

Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling
por: Bae, June Sung, et al.
Publicado: (2018)

Comparative analysis of human embryonic stem cell-derived neural stem cells as an in vitro human model
por: Oh, Jung-Hwa, et al.
Publicado: (2018)

Chemical compound 31002 stimulates cardiomyogenic differentiation of embryonic stem cells
por: Kim, Eun Kyoung, et al.
Publicado: (2011)

The Protective Effects of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in Noise-Induced Hearing Loss of Rats
por: Kim, So Young, et al.
Publicado: (2022)

O-GlcNAcylation of Sox2 at threonine 258 regulates the self-renewal and early cell fate of embryonic stem cells
por: Kim, Dong Keon, et al.
Publicado: (2021)

Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines
por: Kim, Young Mi, et al.
Publicado: (2013)

Cyclin-dependent kinase 1 activity coordinates the chromatin associated state of Oct4 during cell cycle in embryonic stem cells
por: Kim, Hye Ji, et al.
Publicado: (2018)

Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells
por: Shin, Jihoon, et al.
Publicado: (2016)

Fibroblast Growth Factor-4 Enhances Proliferation of Mouse Embryonic Stem Cells via Activation of c-Jun Signaling
por: Kook, Sung-Ho, et al.
Publicado: (2013)

Fluorescence-Based Analysis of Noncanonical Functions of Aminoacyl-tRNA Synthetase-Interacting Multifunctional Proteins (AIMPs) in Peripheral Nerves
por: Kim, Muwoong, et al.
Publicado: (2019)

Ultrastructural comparison of porcine putative embryonic stem cells derived by in vitro fertilization and somatic cell nuclear transfer
por: YOO, Hyunju, et al.
Publicado: (2016)

Isolation of High Purity Mouse Mesenchymal Stem Cells through Depleting Macrophages Using Liposomal Clodronate
por: Song, Ju Han, et al.
Publicado: (2022)

Efficient Generation of Neural Stem Cells from Embryonic Stem Cells Using a Three-Dimensional Differentiation System
por: Yoon, Sang-Hoon, et al.
Publicado: (2021)

Transcriptional Regulation of Human NANOG by Alternate Promoters in Embryonic Stem Cells
por: Das, Satyabrata, et al.
Publicado: (2012)

Histone H1 Depletion Impairs Embryonic Stem Cell Differentiation
por: Zhang, Yunzhe, et al.
Publicado: (2012)

The Effects of Co-Culture of Embryonic Stem Cells with Neural Stem Cells on Differentiation
por: Kim, Ye Rim, et al.
Publicado: (2022)

Functional Fragments of AIMP1-Derived Peptide (AdP) and Optimized Hydrosol for Their Topical Deposition by Box-Behnken Design
por: Lee, Jeong-Jun, et al.
Publicado: (2019)

AIMP3 inhibits cell growth and metastasis of lung adenocarcinoma through activating a miR‐96‐5p‐AIMP3‐p53 axis
por: Ding, Liting, et al.
Publicado: (2021)

The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer
por: Lee, Seon-Hyeong, et al.
Publicado: (2020)

Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells
por: Kim, Chuna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_l45s7da2rrqtkg13v3cpgvghni