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CDC25 Inhibition in Acute Myeloid Leukemia–A Study of Patient Heterogeneity and the Effects of Different Inhibitors

Cell division cycle 25 (CDC25) protein phosphatases regulate cell cycle progression through the activation of cyclin-dependent kinases (CDKs), but they are also involved in chromatin modulation and transcriptional regulation. CDC25 inhibition is regarded as a possible therapeutic strategy for the tr...

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Detalles Bibliográficos
Autores principales: Brenner, Annette K., Reikvam, Håkon, Rye, Kristin Paulsen, Hagen, Karen Marie, Lavecchia, Antonio, Bruserud, Øystein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155411/
https://www.ncbi.nlm.nih.gov/pubmed/28287460
http://dx.doi.org/10.3390/molecules22030446