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A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid

Amentoflavone (C(30)H(18)O(10)) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence effects on many important reactions in th...

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Detalles Bibliográficos
Autores principales: Yu, Sheng, Yan, Hui, Zhang, Li, Shan, Mingqiu, Chen, Peidong, Ding, Anwei, Li, Sam Fong Yau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155574/
https://www.ncbi.nlm.nih.gov/pubmed/28212342
http://dx.doi.org/10.3390/molecules22020299
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author Yu, Sheng
Yan, Hui
Zhang, Li
Shan, Mingqiu
Chen, Peidong
Ding, Anwei
Li, Sam Fong Yau
author_facet Yu, Sheng
Yan, Hui
Zhang, Li
Shan, Mingqiu
Chen, Peidong
Ding, Anwei
Li, Sam Fong Yau
author_sort Yu, Sheng
collection PubMed
description Amentoflavone (C(30)H(18)O(10)) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence effects on many important reactions in the cardiovascular and central nervous system, etc. Over 120 plants have been found to contain this bioactive component, such as Selaginellaceae, Cupressaceae, Euphorbiaceae, Podocarpaceae, and Calophyllaceae plant families. This review paper aims to profile amentoflavone on its plant sources, natural derivatives, pharmacology, and pharmacokinetics, and to highlight some existing issues and perspectives in the future.
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spelling pubmed-61555742018-11-13 A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid Yu, Sheng Yan, Hui Zhang, Li Shan, Mingqiu Chen, Peidong Ding, Anwei Li, Sam Fong Yau Molecules Review Amentoflavone (C(30)H(18)O(10)) is a well-known biflavonoid occurring in many natural plants. This polyphenolic compound has been discovered to have some important bioactivities, including anti-inflammation, anti-oxidation, anti-diabetes, and anti-senescence effects on many important reactions in the cardiovascular and central nervous system, etc. Over 120 plants have been found to contain this bioactive component, such as Selaginellaceae, Cupressaceae, Euphorbiaceae, Podocarpaceae, and Calophyllaceae plant families. This review paper aims to profile amentoflavone on its plant sources, natural derivatives, pharmacology, and pharmacokinetics, and to highlight some existing issues and perspectives in the future. MDPI 2017-02-16 /pmc/articles/PMC6155574/ /pubmed/28212342 http://dx.doi.org/10.3390/molecules22020299 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yu, Sheng
Yan, Hui
Zhang, Li
Shan, Mingqiu
Chen, Peidong
Ding, Anwei
Li, Sam Fong Yau
A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title_full A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title_fullStr A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title_full_unstemmed A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title_short A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid
title_sort review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone, a naturally-occurring biflavonoid
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155574/
https://www.ncbi.nlm.nih.gov/pubmed/28212342
http://dx.doi.org/10.3390/molecules22020299
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