Synthesis and Preliminary Biological Evaluation of Indol-3-yl-oxoacetamides as Potent Cannabinoid Receptor Type 2 Ligands

A small series of indol-3-yl-oxoacetamides was synthesized starting from the literature known N-(adamantan-1-yl)-2-(5-(furan-2-yl)-1-pentyl-1H-indol-3-yl)-2-oxoacetamide (5) by substituting the 1-pentyl-1H-indole subunit. Our preliminary biological evaluation showed that the fluorinated derivative 8...

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Detalles Bibliográficos
Autores principales: Moldovan, Rareş-Petru, Deuther-Conrad, Winnie, Horti, Andrew G., Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155603/
https://www.ncbi.nlm.nih.gov/pubmed/28054997
http://dx.doi.org/10.3390/molecules22010077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155603/
https://www.ncbi.nlm.nih.gov/pubmed/28054997
http://dx.doi.org/10.3390/molecules22010077

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