Intramolecular Hydrogen Bonds in Conformers of Quinine and Quinidine: An HF, MP2 and DFT Study

Quinine is an alkaloid with powerful antimalarial activity, isolated from the bark of Peru’s cinchona trees. Quinidine is an erythro diastereoisomer of quinine also exhibiting antimalarial activity. Conformational studies performed so far had never identified conformers with intramolecular hydrogen...

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Detalles Bibliográficos
Autores principales: Bilonda, Mireille K., Mammino, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155604/
https://www.ncbi.nlm.nih.gov/pubmed/28178218
http://dx.doi.org/10.3390/molecules22020245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155604/
https://www.ncbi.nlm.nih.gov/pubmed/28178218
http://dx.doi.org/10.3390/molecules22020245

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