Effective Synthesis of Nucleosides Utilizing O-Acetyl-Glycosyl Chlorides as Glycosyl Donors in the Absence of Catalyst: Mechanism Revision and Application to Silyl-Hilbert-Johnson Reaction

An effective synthesis of nucleosides using glycosyl chlorides as glycosyl donors in the absence of Lewis acid has been developed. Glycosyl chlorides have been shown to be pivotal intermediates in the classical silyl-Hilbert-Johnson reaction. A possible mechanism that differs from the currently acce...

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Detalles Bibliográficos
Autores principales: Liang, Chengyuan, Ju, Weihui, Ding, Shunjun, Sun, Han, Mao, Gennian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155650/
https://www.ncbi.nlm.nih.gov/pubmed/28067759
http://dx.doi.org/10.3390/molecules22010084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155650/
https://www.ncbi.nlm.nih.gov/pubmed/28067759
http://dx.doi.org/10.3390/molecules22010084

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