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Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity

Artemisinin and synthetic derivatives of dihydroartemisinin are known to possess various biological activities. Post-functionalization of dihydroartemisinin with triazole heterocycles has been proven to lead to enhanced therapeutic potential. By using our newly developed triazolization strategy, a l...

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Detalles Bibliográficos
Autores principales: Jana, Sampad, Iram, Shabina, Thomas, Joice, Hayat, Muhammad Qasim, Pannecouque, Christophe, Dehaen, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155659/
https://www.ncbi.nlm.nih.gov/pubmed/28218680
http://dx.doi.org/10.3390/molecules22020303