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Modeling of the Bioactivation of an Organic Nitrate by a Thiol to Form a Thionitrate Intermediate
Thionitrates (R–SNO(2)) have been proposed as key intermediates in the biotransformation of organic nitrates that have been used for the clinical treatment of angina pectoris for over 100 years. It has been proposed and widely accepted that a thiol would react with an organic nitrate to afford a thi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155724/ https://www.ncbi.nlm.nih.gov/pubmed/28029139 http://dx.doi.org/10.3390/molecules22010019 |