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Synthesis of 16 New Hybrids from Tetrahydropyrans Derivatives and Morita-Baylis-Hillman Adducts: In Vitro Screening against Leishmania donovani

Leishmaniases are a group of neglected tropical diseases (NTDs) caused by protozoan parasites from >20 Leishmania species. Visceral leishmaniasis (VL), also known as kala-aza, is the most severe form of leishmaniasis, usually fatal in the absence of treatment in 95% of cases. The Morita-Baylis-Hi...

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Detalles Bibliográficos
Autores principales: de Oliveira Sousa, Suervy Canuto, da Câmara Rocha, Juliana, de Souza Lima Keesen, Tatjana, da Paz Silva, Everton, de Assis, Priscilla Anne Castro, de Oliveira, João Paulo Gomes, Capim, Saulo Luís, Xavier, Francisco José Seixas, Marinho, Bruno Guimarães, Silva, Fábio Pedrosa Lins, Lima-Junior, Claudio Gabriel, Vasconcellos, Mário Luiz Araújo de Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155752/
https://www.ncbi.nlm.nih.gov/pubmed/28146095
http://dx.doi.org/10.3390/molecules22020207