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Design and Experimental Evolution of trans-Splicing Group I Intron Ribozymes
Group I intron ribozymes occur naturally as cis-splicing ribozymes, in the form of introns that do not require the spliceosome for their removal. Instead, they catalyze two consecutive trans-phosphorylation reactions to remove themselves from a primary transcript, and join the two flanking exons. De...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155759/ https://www.ncbi.nlm.nih.gov/pubmed/28045452 http://dx.doi.org/10.3390/molecules22010075 |