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Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins

In the present study, photoirradiation molecularly imprinted polymer (MIP) with azobenzene was used as a functional monomer for the selective separation of the branched cyclodextrins. The functional monomer 4-methacryloyloxy azobenzene (MAA) and the molecular template 6-O-α-d-maltosyl-β-cyclodextrin...

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Autores principales: Fan, Haoran, Wang, Jinpeng, Meng, Qingran, Xu, Xueming, Fan, Tianming, Jin, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155763/
https://www.ncbi.nlm.nih.gov/pubmed/28230805
http://dx.doi.org/10.3390/molecules22020288
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author Fan, Haoran
Wang, Jinpeng
Meng, Qingran
Xu, Xueming
Fan, Tianming
Jin, Zhengyu
author_facet Fan, Haoran
Wang, Jinpeng
Meng, Qingran
Xu, Xueming
Fan, Tianming
Jin, Zhengyu
author_sort Fan, Haoran
collection PubMed
description In the present study, photoirradiation molecularly imprinted polymer (MIP) with azobenzene was used as a functional monomer for the selective separation of the branched cyclodextrins. The functional monomer 4-methacryloyloxy azobenzene (MAA) and the molecular template 6-O-α-d-maltosyl-β-cyclodextrin (G2-β-CD) were implemented for the molecular imprinting. The core-shell structure of photoirradiation MIP was visualized by the transmission electron microscopy (TEM). With Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), we identified that G2-β-CD was imprinted into the polymer and removed from the MIP. The binding association constant (K(a)) and the maximum number of the binding site (N(max)) were 1.72 × 10(4) M(−1) and 7.93 μmol·g(−1) MIP, respectively. With alternate irradiation at 365 and 440 nm light, the prepared MIP reversibly released and rebound to the G2-β-CD, which resulted in the nearly zero amount of G2-β-CD in the solution. The HPLC results indicated that the purity of G2-β-CD could reach 90.8% after going through MIP. The main finding of our study was that the photoirradiation of MIP was an easy and effective method for the selective separation of the branched cyclodextrins.
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spelling pubmed-61557632018-11-13 Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins Fan, Haoran Wang, Jinpeng Meng, Qingran Xu, Xueming Fan, Tianming Jin, Zhengyu Molecules Article In the present study, photoirradiation molecularly imprinted polymer (MIP) with azobenzene was used as a functional monomer for the selective separation of the branched cyclodextrins. The functional monomer 4-methacryloyloxy azobenzene (MAA) and the molecular template 6-O-α-d-maltosyl-β-cyclodextrin (G2-β-CD) were implemented for the molecular imprinting. The core-shell structure of photoirradiation MIP was visualized by the transmission electron microscopy (TEM). With Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA), we identified that G2-β-CD was imprinted into the polymer and removed from the MIP. The binding association constant (K(a)) and the maximum number of the binding site (N(max)) were 1.72 × 10(4) M(−1) and 7.93 μmol·g(−1) MIP, respectively. With alternate irradiation at 365 and 440 nm light, the prepared MIP reversibly released and rebound to the G2-β-CD, which resulted in the nearly zero amount of G2-β-CD in the solution. The HPLC results indicated that the purity of G2-β-CD could reach 90.8% after going through MIP. The main finding of our study was that the photoirradiation of MIP was an easy and effective method for the selective separation of the branched cyclodextrins. MDPI 2017-02-21 /pmc/articles/PMC6155763/ /pubmed/28230805 http://dx.doi.org/10.3390/molecules22020288 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fan, Haoran
Wang, Jinpeng
Meng, Qingran
Xu, Xueming
Fan, Tianming
Jin, Zhengyu
Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title_full Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title_fullStr Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title_full_unstemmed Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title_short Preparation of Photoirradiation Molecular Imprinting Polymer for Selective Separation of Branched Cyclodextrins
title_sort preparation of photoirradiation molecular imprinting polymer for selective separation of branched cyclodextrins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155763/
https://www.ncbi.nlm.nih.gov/pubmed/28230805
http://dx.doi.org/10.3390/molecules22020288
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