Efficient Synthesis of Novel Pyridine-Based Derivatives via Suzuki Cross-Coupling Reaction of Commercially Available 5-Bromo-2-methylpyridin-3-amine: Quantum Mechanical Investigations and Biological Activities

The present study describes palladium-catalyzed one pot Suzuki cross-coupling reaction to synthesize a series of novel pyridine derivatives 2a–2i, 4a–4i. In brief, Suzuki cross-coupling reaction of 5-bromo-2-methylpyridin-3-amine (1) directly or via N-[5-bromo-2-methylpyridine-3-yl]acetamide (3) wit...

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Detalles Bibliográficos
Autores principales: Ahmad, Gulraiz, Rasool, Nasir, Ikram, Hafiz Mansoor, Gul Khan, Samreen, Mahmood, Tariq, Ayub, Khurshid, Zubair, Muhammad, Al-Zahrani, Eman, Ali Rana, Usman, Akhtar, Muhammad Nadeem, Alitheen, Noorjahan Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155797/
https://www.ncbi.nlm.nih.gov/pubmed/28134790
http://dx.doi.org/10.3390/molecules22020190

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